Circadian Rhythms: Lost in Post-Translation
نویسنده
چکیده
Multiple studies question the necessity of transcription/translation feedback loops for the generation of circadian rhythms. New data emphasize the necessity of proteasomal degradation for circadian rhythmicity in transcriptionally competent cells.
منابع مشابه
Post-transcriptional control of circadian rhythms.
Circadian rhythms exist in most living organisms. The general molecular mechanisms that are used to generate 24-hour rhythms are conserved among organisms, although the details vary. These core clocks consist of multiple regulatory feedback loops, and must be coordinated and orchestrated appropriately for the fine-tuning of the 24-hour period. Many levels of regulation are important for the pro...
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عنوان ژورنال:
- Current Biology
دوره 21 شماره
صفحات -
تاریخ انتشار 2011